Antimicrobial resistance is increasingly becoming a major threat to modern medicine, and multiple efforts should be made to address this major challenge. Antimicrobial susceptibility testing (AST) is an important tool that promises to provide accurate bacterial information, such as minimum inhibitory concentrations (MICs), which determine optimal use of antibiotics and potentially reduce antibiotic resistance. A major remedy is to reduce the misuse or misuse of antibiotics, especially broad-spectrum antibiotics, which are prescribed without definitive clues as to whether and which microbe is causing the infection. Many teams, including my own, are continuously working in this area (e.g. Lab Chip 2016, ChemPlusChem 2017, Trends Biotech 2017, Lab Chip2019, etc.). These new antimicrobial susceptibility testing (AST) methods are being developed to help physicians provide more personalized treatment.
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